Business
First Blood Test to Help Diagnose Alzheimer’s Goes on Sale
Published
5 years agoon
ST. LOUIS, Mis. (AP) — A company has started selling the first blood test to help diagnose Alzheimer’s disease, a leap for the field that could make it much easier for people to learn whether they have dementia. It also raises concern about the accuracy and impact of such life-altering news.
Independent experts are leery because key test results have not been published and the test has not been approved by the U.S. Food and Drug Administration — it’s being sold under more general rules for commercial labs. But they agree that a simple test that can be done in a doctor’s office has long been needed.
It might have spared Tammy Maida a decade of futile trips to doctors who chalked up her symptoms to depression, anxiety or menopause before a $5,000 brain scan last year finally showed she had Alzheimer’s.
“I now have an answer,” said the 63-year-old former nurse from San Jose, California.
If a blood test had been available, “I might have been afraid of the results” but would have “jumped on that” to find out, she said.
More than 5 million people in the United States and millions more around the world have Alzheimer’s, the most common form of dementia. To be diagnosed with it, people must have symptoms such as memory loss plus evidence of a buildup of a protein called beta-amyloid in the brain.
The best way now to measure the protein is a costly PET brain scan that usually is not covered by insurance. That means most people don’t get one and are left wondering if their problems are due to normal aging, Alzheimer’s or something else.
The blood test from C2N Diagnostics of St. Louis aims to fill that gap. The company’s founders include Drs. David Holtzman and Randall Bateman of Washington University School of Medicine, who headed research that led to the test and are included on a patent that the St. Louis university licensed to C2N.
ABOUT THE TEST
The test is not intended for general screening or for people without symptoms — it’s aimed at people 60 and older who are having thinking problems and are being evaluated for Alzheimer’s. It’s not covered by insurance or Medicare; the company charges $1,250 and offers discounts based on income. Only doctors can order the test and results come within 10 days. It’s sold in all but a few states in the U.S. and just was cleared for sale in Europe.
It measures two types of amyloid particles plus various forms of a protein that reveal whether someone has a gene that raises risk for the disease. These factors are combined in a formula that includes age, and patients are given a score suggesting low, medium or high likelihood of having amyloid buildup in the brain.
If the test puts them in the low category, “it’s a strong reason to look for other things” besides Alzheimer’s, Bateman said.
“There are a thousand things that can cause someone to be cognitively impaired,” from vitamin deficiencies to medications, Holtzman said.
“I don’t think this is any different than the testing we do now” except it’s from a blood test rather than a brain scan, he said. “And those are not 100% accurate either.”
ACCURACY CLAIMS
The company has not published any data on the test’s accuracy, although the doctors have published on the amyloid research leading to the test. Company promotional materials cite results comparing the test to PET brain scans — the current gold standard — in 686 people, ages 60-91, with cognitive impairment or dementia.
If a PET scan showed amyloid buildup, the blood test also gave a high probability of that in 92% of cases and missed 8% of them, said the company’s chief executive, Dr. Joel Braunstein.
If the PET scan was negative, the blood test ruled out amyloid buildup 77% of the time. The other 23% got a positive result, but that doesn’t necessarily mean the blood test was incorrect, Braunstein said. The published research suggests it may detect amyloid buildup before it’s evident on scans.
Braunstein said the company will seek FDA approval and the agency has given it a designation that can speed review. He said study results would be published, and he defended the decision to start selling the test now.
“Should we be holding that technology back when it could have a big impact on patient care?” he asked.
WHAT OTHERS SAY
Dr. Eliezer Masliah, neuroscience chief at the U.S. National Institute on Aging, said the government funded some of the work leading to the test as well as other kinds of blood tests.
“I would be cautious about interpreting any of these things,” he said of the company’s claims. “We’re encouraged, we’re interested, we’re funding this work but we want to see results.”
Heather Snyder of the Alzheimer’s Association said it won’t endorse a test without FDA approval. The test also needs to be studied in larger and diverse populations.
“It’s not quite clear how accurate or generalizable the results are,” she said.
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Business
Orlando Regional REALTOR Association Event Highlights Orange County Growth, Housing Trends and Economic Outlook
Published
1 month agoon
April 19, 2026By
Willie DavidORLANDO, Fla. (FNN) — The Orlando Regional REALTOR Association (ORRA) hosted its second annual State of Real Estate event for Orange County on April 17, bringing together industry professionals, policymakers and community leaders to examine the region’s housing market and economic outlook.
Held at ORRA’s headquarters in Orlando, the event focused on the evolving dynamics of residential and commercial real estate across Central Florida. Discussions centered on housing affordability, economic growth and long-term regional development.
Speakers and Panelists
- Lawrence Yun — Chief Economist, National Association of REALTORS
- Maria Henson — Senior Director of Market Research & Insights, Visit Orlando
- Racquel Asa — Head of External Affairs, Central Florida Expressway Authority
- Amy Mercado — Property Appraiser, Orange County
- Chris Atwell — Moderator, 2026 ORRA President
Industry experts said Central Florida’s economy continues to grow, though at a more measured pace. While housing and stock market wealth remain near record highs, job growth is softening, consumer sentiment has declined and loan defaults are rising — creating a market shaped by mixed signals.
Panelists noted the housing market has shifted into a more stable phase compared to the rapid growth seen during 2020 and 2021, with more balance and sustainable conditions.
Despite short-term fluctuations, long-term fundamentals remain strong. Orange County’s tax base has grown significantly since 2023, while the broader Central Florida region has experienced a 23% population increase over the past decade, with more than 1,200 people moving to the area each week.
Infrastructure and tourism were also highlighted as key drivers of future growth. Officials pointed to major roadway investments by the Central Florida Expressway Authority and the region’s continued strength as a tourism hub, drawing more than 75 million visitors in 2024.
“We’re operating in a global economy where interest rates, supply chains and migration policies all influence what happens at the local level,” said ORRA CEO Cliff Long.
Economic Trends Show Mixed Signals
Experts emphasized that strong asset values are being offset by softer job growth and declining consumer confidence.
Housing Market Enters Stable Phase
The market has transitioned from pandemic-driven volatility to a more balanced and sustainable pace.
Growth, Infrastructure and Tourism Drive Future
Population growth, infrastructure investment and tourism continue to support long-term expansion in Central Florida.
ORRA’s Impact and Benefits on the Real Estate Industry
The Orlando Regional REALTOR Association provides critical market insights, advocacy and professional resources for REALTORS® across Central Florida. Its events foster collaboration between industry leaders, policymakers and the community, helping guide responsible growth, inform housing policy and strengthen the regional real estate market.
Business
Walmart’s Road to Open Call Returns to Orlando, Offering Small Businesses Access to National Retail Opportunities
Published
1 month agoon
April 15, 2026By
Willie David
ORLANDO, Fla. (FNN) — Walmart, in partnership with the Hispanic Chamber of Metro Orlando, will host the 2026 Walmart Road to Open Call pitch event on May 21 in Orlando, offering small businesses the opportunity to present their products directly to Walmart buyers.
The Orlando event is the only Florida stop in 2026 and is part of a nationwide initiative designed to support small business growth, expand supplier diversity and strengthen U.S. manufacturing.
OPPORTUNITY FOR SMALL BUSINESSES
The Road to Open Call serves as a pathway for entrepreneurs to connect with Walmart’s sourcing team, refine their pitches and prepare for the company’s annual Open Call event in Bentonville, Arkansas.
Applications are open through May 1 at 10 p.m. EST. A select group of applicants will be chosen to participate in the Orlando event, where each business will receive a 30-minute, one-on-one pitch meeting with a Walmart buyer, along with feedback and mentorship.
Top participants may earn a fast pass to Walmart’s annual Open Call, where they can pitch for potential placement in Walmart stores or online.
FOCUS ON U.S.-MADE PRODUCTS
Walmart’s Open Call is the company’s largest sourcing event for products made, grown or assembled in the United States. The program is open to businesses across industries, including food and beverage, beauty, safety and consumer goods.
“The Road to Open Call provides a powerful platform for small businesses to grow and scale,” said Mark Espinoza, senior director of public affairs at Walmart. “By connecting entrepreneurs directly with our sourcing teams, we’re helping bring innovative, U.S.-made products to customers while supporting American jobs and local economies.”
LOCAL IMPACT AND ECONOMIC GROWTH
Local leaders say the initiative strengthens both entrepreneurship and the regional economy.
“We are proud to join forces with Walmart for the second consecutive year to bring this opportunity to the business community,” said Pedro Turushina, president and CEO of the Hispanic Chamber of Metro Orlando. “This initiative supports entrepreneurs and helps small businesses access national retail opportunities.”
Since launching in 2014, Walmart’s Open Call has helped thousands of small and midsize businesses become suppliers, while more than 85% of Walmart shoppers report valuing U.S.-made products.
Business
AdventHealth Opens 2026 Community Impact Grants to Address Central Florida Health Needs
Published
1 month agoon
April 15, 2026By
Willie DavidORLANDO, Fla. (FNN) — AdventHealth is now accepting applications for its 2026 Community Impact Grants, aimed at supporting nonprofit organizations working to address critical health needs across Central Florida.
The grant program partners with community-based organizations to expand initiatives that improve quality of life and promote long-term sustainability. Eligible nonprofits serving residents in Orange, Osceola, Seminole and South Lake counties are encouraged to apply.
Applications are open from March 30 through April 16, with funding expected to begin Jan. 1, 2027.
FOCUS ON COMMUNITY HEALTH NEEDS
The grants are guided by Central Florida’s Community Health Needs Assessment, which identifies key challenges impacting residents’ well-being.
“Our annual Community Impact Grants are guided by Central Florida’s Community Health Needs Assessment to ensure we are investing meaningfully where our neighbors need us most,” said Tricia Edris, senior vice president of innovation and partnerships for AdventHealth Central Florida. “We are honored to align our resources and stand as partners to create measurable, lasting impact across the region.”
PRIORITY AREAS FOR FUNDING
The 2026 grant cycle will focus on three key areas:
- Housing instability
- Transportation
- Food insecurity
These priorities reflect social determinants of health that can significantly influence a person’s ability to live a healthy and stable life. Community organizations often serve as the first line of support for residents facing these challenges.
COMMUNITY IMPACT AND PARTNERSHIPS
Past grant recipients say the program has helped expand opportunities for residents. Crystal Davidson highlighted the impact of the initiative on workforce development.
“Schools and colleges often don’t have the funding to provide introductory workforce programs that expose students to new career opportunities,” Davidson said. “Through partnership grants like the one AdventHealth is providing, we’re able to give young people hands-on experiences that help them discover their potential and build a path toward a meaningful career.”
AdventHealth will also host an informational webinar to guide organizations through eligibility requirements, funding priorities and the application process. Interested applicants can learn more and apply through the AdventHealth website.