Business
Pfizer says COVID-19 vaccine is looking 90% effective
Published
6 years agoon
Pfizer said Monday that an early peek at the data on its coronavirus vaccine suggests the shots may be a surprisingly robust 90% effective at preventing COVID-19, putting the company on track to apply later this month for emergency-use approval from the Food and Drug Administration.
The announcement, less than a week after a presidential election that was seen as a referendum on President Donald Trump’s handling of the crisis, was a rare and major piece of encouraging news lately in the battle against the scourge that has killed more than 1.2 million people worldwide, including almost a quarter-million in the United States alone, with confirmed infections in the U.S. expected to eclipse 10 million on Monday.
“We’re in a position potentially to be able to offer some hope,” Dr. Bill Gruber, Pfizer’s senior vice president of clinical development, told The Associated Press. “We’re very encouraged.”
Dr. Anthony Fauci, the government’s top-infectious disease expert, said the results suggesting 90% effectiveness are “just extraordinary,” adding: “Not very many people expected it would be as high as that.”
“It’s going to have a major impact on everything we do with respect to COVID,” Fauci said.
Pharmaceutical companies and various countries are in a global race to develop a vaccine against the virus. Fauci said that the Pfizer vaccine and virtually all others in testing target the spike protein the coronavirus uses to infect cells, so the results validate that approach.
Monday’s announcement doesn’t mean a vaccine is imminent: This interim analysis, from an independent data monitoring board, looked at 94 infections recorded so far in a study that has enrolled nearly 44,000 people in the U.S. and five other countries. Some participants got the vaccine, while others got dummy shots.
Pfizer Inc. did not provide any more details about those infections and cautioned that the initial protection rate might change by the time the study ends. Even revealing such early data is highly unusual.
Authorities have stressed it’s unlikely any vaccine will arrive much before the end of the year, and initial supplies will be rationed.
“We need to see the data, but this is extremely promising,” said Dr. Jesse Goodman of Georgetown University, former chief of the FDA’s vaccine division. He ticked off many questions still to be answered, including how long the vaccine’s effects last and whether it protects older people as well as younger ones.
If Pfizer’s vaccine ultimately pans out, “it’s going to be a while before this has a major impact at the population level,” Goodman said.
Marylyn Addo, head of the tropical medicine unit at UKE hospital in Hamburg, Germany, said the interim results were “an interesting first signal,” but questions remain.
Global markets, already buoyed by the victory of President-elect Joe Biden, exploded on the news from Pfizer. Major markets in Europe, where infections have soared, were up 5%. In the U.S., the S%P 500 surged 3.7% after the opening bell, and the Dow Jones Industrial Average was up more than 1,300 points.
Trump, who had suggested during the presidential campaign that a vaccine could be ready by Election Day, tweeted on Monday: “STOCK MARKET UP BIG, VACCINE COMING SOON. REPORT 90% EFFECTIVE. SUCH GREAT NEWS!”
The timing is likely to feed unsubstantiated suspicions from Trump supporters that the pharmaceutical industry was withholding the news until after the election. Donald Trump Jr. tweeted: “The timing of this is pretty amazing. Nothing nefarious about the timing of this at all right?”
Pfizer Chairman and CEO Albert Bourla said on CNBC that the election was always an artificial deadline and that the data was going to be ready when it was ready. The independent data monitors met on Sunday, analyzing the COVID-19 test results so far and notifying Pfizer.
“I am very happy,” Bourla said, “but at the same time, sometimes I have tears in my eyes when I realize that this is the end of nine months, day-and-night work of so many people and how many people, billions, invested hopes on this.”
He added: “I never thought it would be 90%.”
Earlier this year, Fauci said he would be happy with a COVID-19 vaccine that was 60% effective. Scientists have warned for months that any COVID-19 shot may be only as good as flu vaccines, which are about 50% effective and require yearly shots.
The coronavirus shots, made by Pfizer and its German partner BioNTech, are among 10 possible vaccine candidates in late-stage testing around the world — four of them so far in huge studies in the U.S. Another U.S. company, Moderna Inc., also has said it hopes to be able to file an application with the FDA later this month.
Volunteers in the final-stage studies, and the researchers, don’t know who received the real vaccine or a dummy shot. But a week after their second required dose, Pfizer’s study began counting the number who developed COVID-19 symptoms and were confirmed to have the coronavirus.
Because the study hasn’t ended, Gruber couldn’t say how many in each group had infections. But the math suggests that almost all the infections counted so far had to have occurred in people who got the dummy shots.
Pfizer doesn’t plan to stop its study until it records 164 infections among all the volunteers, a number that the FDA has agreed is enough to tell how well the vaccine is working. The agency has made clear that any vaccine must be at least 50% effective.
No participant so far has become severely ill, Gruber said. Nor could he provide a breakdown of how many of the infections had occurred in older people, who are at highest risk from COVID-19.
Participants were tested only if they developed symptoms, leaving unanswered whether vaccinated people could get infected but show no symptoms and unknowingly spread the virus.
FDA has told companies they must track half their participants for side effects for at least two months, the time period when problems typically crop up. Pfizer expects to reach that milestone later this month, but said Monday no serious safety concerns have been reported.
Because the pandemic is still raging, manufacturers hope to seek permission from governments around the world for emergency use of their vaccines while additional testing continues — allowing them to get to market faster than normal but raising concerns about how much scientists will know about the shots.
The FDA’s scientific advisers last month said they worry that allowing emergency use of a COVID-19 vaccine could damage confidence in the shots and make it harder to ever find out how well they really work. Those advisers said it’s critical these massive studies are allowed to run to completion.
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Business
AdventHealth Recruiting Nurses, Technologists and Clinical Professionals at 8 Central Florida Locations
Published
3 hours agoon
September 8, 2026The Sept. 9 regional hiring event will connect nurses, imaging and laboratory professionals, respiratory therapists and other clinical workers with hiring managers at eight AdventHealth locations.
ORLANDO, Fla. (FNN) — AdventHealth will hold a regional hiring event Wednesday, Sept. 9, at eight locations across Central Florida as the health system looks to expand its clinical workforce to meet growing demand for patient care.
The hiring events will run from 9 a.m. to 1 p.m. and give nurses, technologists and other clinical professionals an opportunity to meet directly with hiring managers and clinical leaders, participate in on-site interviews and potentially receive same-day job offers for select positions, according to AdventHealth.
The recruitment effort comes as Central Florida’s population growth continues to increase demand for health care services across hospitals, emergency departments and other care sites.
High-Demand Clinical Positions
AdventHealth said career opportunities are available across several high-need clinical areas, including:
- Nursing
- Imaging
- Laboratory
- Respiratory care
- Surgical services
- Other clinical specialties
The regional format allows applicants to explore opportunities at multiple AdventHealth facilities while connecting directly with the people responsible for hiring and clinical operations.
Eight Central Florida Hiring Locations
Hiring events will be held simultaneously at the following locations from 9 a.m. to 1 p.m. Wednesday, Sept. 9:
AdventHealth Altamonte Springs
601 E. Altamonte Drive, Altamonte Springs
Chatlos Classrooms
AdventHealth Apopka
2100 Ocoee Apopka Road, Apopka
Vyas Conference Rooms
AdventHealth Celebration
400 Celebration Place, Celebration
Mangrove Conference Rooms
AdventHealth East Orlando
7727 Lake Underhill Road, Orlando
Precedo Conference Rooms
AdventHealth Kissimmee
2450 N. Orange Blossom Trail, Kissimmee
Woodlands Conference Rooms
AdventHealth Orlando, AdventHealth for Women & Children
601 E. Rollins St., Orlando
Alden Conference Room
AdventHealth Winter Park
200 N. Lakemont Ave., Winter Park
First Floor Conference Center
AdventHealth Winter Garden
2000 Fowler Grove Blvd., Winter Garden
First Floor Conference Rooms
Central Florida Growth Driving Recruitment
AdventHealth said the regional recruitment initiative is designed to strengthen clinical teams as the health system expands access to care throughout Central Florida.
Hiring across multiple hospitals and specialties also reflects the range of health care workers needed to support growing communities — from bedside nurses and respiratory professionals to diagnostic imaging, laboratory and surgical-services teams.
For qualified candidates, the possibility of interviewing directly with hiring managers and receiving a same-day offer for select positions could also shorten the traditional hiring process.
How to Register
Health care professionals interested in attending can register through the official AdventHealth Central Florida Hiring Event page.
Event: AdventHealth Central Florida Regional Hiring Event
Date: Wednesday, Sept. 9, 2026
Time: 9 a.m.-1 p.m.
Locations: Eight AdventHealth facilities across Central Florida
FNN Community & Business
The regional hiring initiative represents a significant employment opportunity for Central Florida’s health care workforce while highlighting the continued demand for clinical professionals as the region’s population and health care needs expand.
Business
DOJ, DOT and DHS Launch Nationwide Crackdown on CDL Fraud, Trucking Schools and Unqualified Drivers
Published
12 hours agoon
September 8, 2026Federal agencies say the new Joint Task Force Crossroads of America will target fraudulent CDL training and testing, identity and document fraud, unauthorized employment and suspected criminal activity across the commercial trucking industry.
DETROIT (FNN) — The Justice, Transportation and Homeland Security departments have launched a sweeping federal initiative targeting alleged fraud and public-safety violations in the commercial trucking industry, including questionable driver training, commercial driver’s license testing, identity fraud and suspected criminal activity.
Eight U.S. attorneys joined federal transportation and homeland security officials Aug. 31 to announce Joint Task Force Crossroads of America, a multistate law enforcement partnership initially bringing together U.S. attorney’s offices in Illinois, Indiana, Michigan and Ohio with federal, state and local agencies.
The initiative brings together DOJ, the Department of Transportation, Department of Homeland Security, Federal Motor Carrier Safety Administration and other law enforcement agencies.
Among the most immediate actions, FMCSA announced the emergency removal of more than 110 commercial driver training providers associated with more than 5,000 drivers who failed federal English-language proficiency requirements. The agency is also proposing removal of more than 160 additional training providers and launching a nationwide audit of third-party CDL skills testers.
DHS, meanwhile, announced enforcement activity involving more than 200 driving schools and related businesses across 23 states.
Federal Government Targets CDL Fraud
Federal officials say the initiative is designed to identify fraudulent training and licensing practices while determining whether trucking companies, schools, testing operations or other businesses are circumventing federal requirements.
Attorney General Todd Blanche said DOJ will work with federal, state and local partners to investigate and prosecute alleged fraud affecting highway safety.
“The safety of American roadways affects everyone across the country,” Blanche said in the federal announcement.
Transportation Secretary Sean P. Duffy said federal transportation regulators need law enforcement support to pursue suspected fraud involving training schools and other participants in the commercial licensing system.
The government’s announcement also included broader claims by administration officials concerning immigration enforcement and highway safety. Those statements represent the administration’s characterization of the problem; the specific enforcement actions announced by FMCSA focus on compliance with federal commercial-driver training, testing and qualification requirements.
110 CDL Training Providers Face Emergency Removal
FMCSA said it examined roadside inspection records involving commercial drivers cited for failing federal English-language proficiency requirements and compared those records with its Training Provider Registry.
That analysis identified training providers that repeatedly certified drivers who subsequently failed the federal requirement, according to the agency.
FMCSA said it will emergency-remove more than 110 Entry-Level Driver Training providers from its registry. The affected providers must cease federally recognized training operations, including classroom and behind-the-wheel instruction.
The government says those schools are associated with more than 5,000 drivers who failed English-language proficiency tests.
Removal from the federal registry is an administrative action and should not, by itself, be characterized as a criminal conviction or finding of criminal fraud.
40-State Investigation Finds Training Problems
The enforcement campaign extends beyond the 110 providers.
FMCSA said it deployed 175 investigators across 40 states in July to conduct nearly 400 investigations of entry-level driver training providers.
According to the agency, investigators identified problems including instructors who lacked appropriate licenses, inadequate facilities for required driving maneuvers and missing assessment records.
One provider allegedly claimed its classroom operated from a school bus located inside the back of a trailer, according to FMCSA.
The investigations resulted in more than 160 notices of proposed removal from the federal Training Provider Registry.
FMCSA further said drivers certified by those providers have been linked to 239 commercial motor vehicle-related fatalities.
That figure warrants careful distinction: the agency’s release describes the drivers as linked to those fatalities; it does not establish from that statistic alone that training deficiencies caused each crash.
Nationwide Audit of CDL Skills Testers
Federal regulators are also turning their attention to the people and organizations administering commercial driving tests.
FMCSA announced a nationwide audit of third-party CDL skills testers and state oversight of those testers.
The agency said more than 28,000 commercial drivers have been placed out of service for English-language proficiency violations since June 2025. FMCSA argues that the number raises concerns about whether testing and state oversight are consistently enforcing federal requirements.
States found substantially out of compliance with federal CDL requirements can face corrective action and, eventually, financial consequences.
According to FMCSA, unresolved substantial noncompliance can result in withholding of federal highway funds—up to 4% initially and potentially 8% in subsequent years. Serious deficiencies can also lead toward decertification of a state’s CDL program.
DHS Targets More Than 200 Driving Schools
DHS is conducting a parallel criminal-investigation and immigration-enforcement effort.
Homeland Security Investigations said its initiative is examining suspected CDL fraud, unauthorized employment, identity-document fraud, financial crimes, money laundering and labor exploitation, along with potential connections to human smuggling, drug trafficking and cartel activity.
Those categories describe investigative targets and potential violations identified by DHS; they do not mean every school, trucking company or driver contacted by investigators has committed a crime.
According to the federal announcement, HSI planned coordinated activity involving more than 200 driving schools across 23 states and said more than 1,000 business leads had been distributed to investigators.
Field offices had also issued more than 80 notices of inspection and opened multiple investigations, according to DHS.
Investigations Include DMV Employees, Medical Certifications and Trucking Companies
Federal authorities disclosed several categories of ongoing investigations.
HSI said investigators are examining allegations that some state motor vehicle employees accepted payments to help applicants circumvent driver’s license and CDL requirements.
Other investigations involve suspected misuse of B-1/B-2 visa holders for domestic cargo transportation, potentially improper medical certifications, identity fraud and alleged labor exploitation involving visa holders.
DHS also said investigators are examining possible shell companies, financial crimes and transportation businesses potentially connected to broader criminal activity.
Because many of these matters remain investigations, allegations of misconduct have not necessarily resulted in criminal charges or convictions.
Federal Trucking Enforcement Reaches Florida
The federal initiative also includes activity in Florida.
According to the government’s announcement, DHS’s Enforcement and Removal Operations Miami Field Office coordinated an operation with the Florida Department of Transportation, FMCSA and commercial vehicle enforcement authorities during the week of Aug. 24.
Other coordinated operations were identified in Illinois, Indiana, Maine, Michigan and Wisconsin.
DHS also identified several broader enforcement initiatives involving commercial transportation, including Operation ICE Wall, Operation Guardrail and Operation Freightliner.
What It Means for Trucking Companies and CDL Schools
The initiative significantly expands federal scrutiny beyond individual commercial drivers.
Training schools could face removal from FMCSA’s registry, while third-party testers will face a nationwide audit. State licensing agencies could also come under federal review if regulators identify systemic compliance failures.
Trucking companies may face additional scrutiny involving driver qualifications, employment authorization, federal employment records and compliance with commercial vehicle regulations.
At the same time, the government’s actions distinguish between administrative enforcement and criminal prosecution. A provider’s removal from a federal training registry does not automatically establish criminal fraud, while criminal cases require prosecutors to establish violations under applicable law.
Joint Task Force Brings Multiple Agencies Together
Joint Task Force Crossroads of America combines the U.S. attorney’s offices in Illinois, Indiana, Michigan and Ohio with agencies including FMCSA, FBI, Drug Enforcement Administration, Homeland Security Investigations, Immigration and Customs Enforcement and Bureau of Alcohol, Tobacco, Firearms and Explosives.
Eight U.S. attorneys participated in the announcement, representing federal districts in Michigan, Indiana, Ohio and Illinois.
Federal officials say the task force’s goals include reducing highway fatalities and serious injuries, identifying criminal networks, deterring fraudulent trucking practices and improving coordination among federal, state and local authorities.
What’s Next?
FMCSA is expected to proceed with the emergency removal of the identified training providers while continuing proposed-removal proceedings involving more than 160 others.
Federal transportation officials will also conduct the nationwide examination of third-party CDL skills testers and state oversight programs.
DHS and HSI investigations into suspected licensing fraud, unauthorized employment, document fraud and related financial crimes are continuing, while the newly established DOJ task force provides a mechanism for federal prosecutors and law enforcement agencies to coordinate potential criminal cases.
The next major question will be how many of the regulatory investigations ultimately produce administrative sanctions, license actions or federal criminal charges.
For drivers, trucking companies and CDL schools, the announcement signals that federal enforcement is expanding from roadside driver inspections into the broader system responsible for training, testing, licensing and employing commercial drivers.
Business
Amazon Cargo Jet Overruns Miami Airport Runway by 1,300 Feet, Killing 5 as NTSB Investigates
Published
13 hours agoon
September 8, 2026Federal investigators recovered both flight recorders after the Boeing 767 operated by 21 Air for Amazon struck vehicles and traveled about 1,300 feet beyond the runway at Miami International Airport.
MIAMI, Fla. (FNN) — Federal investigators are working to determine why an Amazon cargo jet overran a runway at Miami International Airport by about 1,300 feet Sunday, struck vehicles inside and outside the airport perimeter and crashed, killing five people and injuring at least five others.
The Boeing 767, operated by 21 Air LLC for Amazon, was arriving from San Juan, Puerto Rico, when it overran the runway at about 2 p.m. Sunday. It was the aircraft’s third flight of the day, according to investigators.
National Transportation Safety Board Chair Jennifer Homendy described the crash site Monday as an area of extensive devastation and debris.
Investigators have recovered both the flight data recorder and cockpit voice recorder, which could provide critical information about the aircraft’s approach, touchdown, speed, braking performance and crew communications.
The NTSB has not determined the probable cause of the crash.
NTSB: Jet Struck Vehicles After Leaving Runway
The five people killed were in two vehicles struck by the aircraft after it left the runway, according to the NTSB.
Investigators said the jet first struck a 2021 white Ford Econoline van owned by Professional Ocean Service Corp., an airline cleaning contractor. Seven people were inside the van.
The aircraft then broke through an airport perimeter fence and struck a Toyota Corolla Cross outside airport property.
The jet continued through another fence near an area where Tesla robotaxis were stationed before coming to rest, according to Homendy.
The crash left a large debris field that investigators are documenting as they reconstruct the aircraft’s path.
Five Killed, At Least Five Injured
The human toll extends beyond the aviation and airport investigation.
According to the NTSB, all five fatalities were among people in the two vehicles struck during the runway overrun. At least five other people were injured.
The circumstances put particular attention on what happened after the aircraft left the paved runway and traveled beyond the airport boundary.
Investigators will examine the entire accident sequence before determining what factors contributed to the fatalities.
Flight Recorders Recovered as NTSB Investigates Cause
The central question remains unanswered: Why couldn’t the aircraft stop before reaching the end of the runway?
Homendy cautioned Monday that investigators would not determine probable cause while working at the scene.
The NTSB is examining whether the aircraft touched down too far along the runway to stop safely and whether the crew should have abandoned the landing and performed a go-around. Investigators are also expected to analyze the aircraft’s speed, braking performance, mechanical condition, weather and runway conditions.
Video of the landing is also expected to play an important role in reconstructing the sequence of events.
The flight data recorder can provide technical information about the aircraft’s speed, altitude, control inputs and systems. The cockpit voice recorder can help investigators establish crew communications and other conditions inside the cockpit during the final phase of the flight.
Investigators will combine that evidence with wreckage examinations, maintenance records, air traffic control information, weather data, surveillance video and witness interviews.
Could the Miami Crash Have Been Prevented?
It is too early to determine.
The NTSB has not concluded that pilot actions, mechanical problems, weather, runway conditions or airport infrastructure caused or contributed to the accident.
One issue under scrutiny is the protection available when an aircraft overruns a runway.
Miami International Airport does not have the type of aircraft arresting system installed at some airports, according to AP reporting. MIA instead has a 1,000-foot runway safety buffer and complies with applicable requirements.
That distinction is important: The absence of an arresting system does not establish that airport infrastructure caused the crash or fatalities.
Investigators will need to determine first why the aircraft overran the runway and then whether different safety measures could have prevented the accident or reduced its severity.
The findings could eventually lead to recommendations involving aircraft operations, runway-overrun protection, airport infrastructure or carrier procedures — but any such conclusions would come after the evidence is analyzed.
Amazon-21 Air Safety Relationship Under Review
Another significant part of the investigation will focus on the relationship between Amazon and 21 Air.
The aircraft was carrying cargo for Amazon but was operated by 21 Air.
Homendy said investigators want to understand the responsibilities of each company, including what safety provisions are contained in contracts, policies and operating arrangements.
That examination could help establish how operational and safety responsibilities were divided between the cargo customer and the airline operating the aircraft.
Amazon has said it is cooperating with the investigation.
Crash Causes Major Disruptions at Miami International Airport
The crash also caused significant disruptions at one of the nation’s busiest aviation gateways.
More than 160 flights were canceled and nearly 325 delayed by late Sunday, according to FlightAware data reported by The Associated Press.
Disruptions continued Monday as aircraft and flight crews remained out of position.
Miami International Airport reported that two of its four runways remained closed and advised passengers to contact their airlines before traveling to the airport.
The closures are especially significant because of MIA’s enormous passenger and cargo operations.
The airport handled approximately 55.3 million passengers and 3.4 million U.S. tons of freight in 2025, according to official MIA statistics. The airport has four runways and recorded nearly 499,000 commercial aircraft movements last year.
That makes prolonged runway restrictions potentially consequential for passenger travel, international commerce and South Florida’s logistics network.
What’s Next?
NTSB investigators are expected to continue documenting the wreckage, examining the aircraft and runway, interviewing witnesses and reviewing operational and maintenance records.
Analysis of the cockpit voice and flight data recorders will be particularly important in determining where the aircraft touched down, how fast it was traveling, how much runway remained and how the aircraft’s braking and other systems performed.
Investigators will also examine weather and runway conditions, flight crew actions, air traffic control communications and the Amazon-21 Air operating relationship.
The NTSB’s investigation process separates the collection of factual evidence from its eventual determination of probable cause. The agency maintains public investigation records and dockets as cases progress.
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